KD-Validated PIN1 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PIN1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:400-1:2,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PIN1; Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1; Dod; Protein (Peptidyl-Prolyl Cis/Trans Isomerase) NIMA-Interacting 1; Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 1; Protein Interacting With Never In Mitosis A1; Parvulin PIN1; Rotamase Pin1; PPIase Pin1; EC 5.2.1.8; Peptidyl-Prolyl Cis-Trans Isomerase Pin1; UBL5 Background: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011] Research Area: Epigenetics and Nuclear Signaling