KD-Validated PNPO Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PNPO Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:400-1:2,000 Alternative Names of Immunogen:PNPO; Pyridoxamine 5'-Phosphate Oxidase; PDXPO; Pyridoxal 5'-Phosphate Synthase; Pyridoxine 5'-Phosphate Oxidase; Pyridoxine-5'-Phosphate Oxidase; Pyridoxamine-Phosphate Oxidase; EC 1.4.3.5; Epididymis Secretory Sperm Binding Protein; Epididymis Secretory Protein Li 302; HEL-S-302 Background: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008] Research Area: Neuroscience,Signal Transduction,Metabolism