KD-Validated PPM1B Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PPM1B Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:100-1:1,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PPM1B; Protein Phosphatase, Mg2+/Mn2+ Dependent 1B; PP2CB; PPC2BETAX; PP2CBETA; Protein Phosphatase 1B; EC 3.1.3.16; PP2C-Beta; Protein Phosphatase 1B (Formerly 2C), Magnesium-Dependent, Beta Isoform; Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B; Protein Phosphatase 2C, Beta Isoform; Protein Phosphatase 2C-Like Protein; Protein Phosphatase 2C Isoform Beta; PP2C-Beta-X Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008] Research Area: Cell Biology