

KVAb00275-50ul · 50ul
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Description
EnkiLife offers the KD-Validated PPP2R1B Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000 Alternative Names of Immunogen:PPP2R1B; Protein Phosphatase 2 Scaffold Subunit Abeta; PP2A-Abeta; PR65B; Serine/Threonine-Protein Phosphatase 2A 65 KDa Regulatory Subunit A Beta Isoform; Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit A (PR 65), Beta Isoform; Protein Phosphatase 2, Structural/Regulatory Subunit A, Beta; Protein Phosphatase 2A, Regulatory Subunit A, Beta Isoform; Protein Phosphatase 2, Regulatory Subunit A, Beta; Protein Phosphatase 2 Regulatory Subunit A, Beta; PP2A Subunit A Isoform PR65-Beta; PP2A Subunit A Isoform R1-Beta; PP2A-A-Beta Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] Research Area: Signal Transduction







