KD-Validated PRKAG1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PRKAG1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:PRKAG1; Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1; Protein Kinase, AMP-Activated, Gamma 1 Non-Catalytic Subunit; 5'-AMP-Activated Protein Kinase Subunit Gamma-1; AMPK Gamma1; 5'-AMP-Activated Protein Kinase, Gamma-1 Subunit; AMPK Subunit Gamma-1; AMPK Gamma-1 Chain; AMPKG; AMPKg Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism