KD-Validated PRMT1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PRMT1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PRMT1; Protein Arginine Methyltransferase 1; HRMT1L2; HCP1; ANM1; HMT1 (HnRNP Methyltransferase, S. Cerevisiae)-Like 2; Histone-Arginine N-MethyltransferasePRMT1; Protein Arginine N-Methyltransferase 1; Interferon Receptor 1-Bound Protein 4; Highly Conserved Protein 1; IR1B4; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase 1-Like 2; HMT1 HnRNP Methyltransferase-Like 2 (S. Cerevisiae); EC 2.1.1.319; EC 2.1.1.77; EC 2.1.1; HMT2 Background: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Cancer