KD-Validated PRMT6 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PRMT6 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Protein Arginine Methyltransferase 6; HRMT1L6; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 6; Histone-Arginine N-Methyltransferase PRMT6; Protein Arginine N-Methyltransferase 6; FLJ10559; HMT1 HnRNP Methyltransferase-Like 6 (S. Cerevisiae); HMT1 HnRNP Methyltransferase-Like 6; EC 2.1.1.319 Background: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011] Research Area: Epigenetics and Nuclear Signaling