KD-Validated PSMB10 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PSMB10 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PSMB10; Proteasome 20S Subunit Beta 10; LMP10; MECL1; Proteasome (Prosome, Macropain) Subunit, Beta Type, 10; Multicatalytic Endopeptidase Complex Subunit MECl-1; Proteasome Subunit Beta Type-10; Low Molecular Mass Protein 10; Proteasome Subunit Beta 10; Proteasome Subunit Beta-2i; Macropain Subunit MECl-1; Proteasome MECl-1; EC 3.4.25.1; MGC1665; Beta2i; Proteasome Catalytic Subunit 2i; Proteasome Subunit Beta 7i; Proteasome Subunit Beta2i; Proteasome Subunit MECL1; Proteasome Subunit Β2i; PRAAS5; BETA2I Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008] Research Area: Immunology,Cell Biology