KD-Validated PSMD4 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PSMD4 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PSMD4; Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4; AF; Rpn10; AF-1; S5A; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4; 26S Proteasome Non-ATPase Regulatory Subunit 4; 26S Proteasome Regulatory Subunit S5A; Proteasome 26S Subunit, Non-ATPase 4; Multiubiquitin Chain-Binding Protein; Antisecretory Factor 1; MCB1; ASF; 26S Proteasome Regulatory Subunit RPN10; S5a/Antisecretory Factor Protein; Angiocidin; PUB-R5 Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008] Research Area: Cancer