KD-Validated PTPN11 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PTPN11 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PTPN11; Protein Tyrosine Phosphatase Non-Receptor Type 11; SH-PTP2; PTP2C; BPTP3; SHP-2; SHP2; SH2 Domain-Containing Protein Tyrosine Phosphatase 2; Tyrosine-Protein Phosphatase Non-Receptor Type 11; Protein-Tyrosine Phosphatase 1D; Protein-Tyrosine Phosphatase 2C; EC 3.1.3.48; SH-PTP3; PTP-1D; NS1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Noonan Syndrome 1; METCDS; SHPTP2; PTP-2C; JMML; Shp2; CFC Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016] Research Area: Signal Transduction,Neuroscience