KD-Validated RBBP4 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated RBBP4 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:RB Binding Protein 4, Chromatin Remodeling Factor; Retinoblastoma-Binding Protein 4; RbAp48; NURF55; Lin-53; Nucleosome-Remodeling Factor Subunit RBAP48; Chromatin Assembly Factor I P48 Subunit; Chromatin Assembly Factor 1 Subunit C; Retinoblastoma-Binding Protein P48; Histone-Binding Protein RBBP4; CAF-I 48 KDa Subunit; CAF-1 Subunit C; CAF-I P48; RBBP-4; Chromatin Assembly Factor/CAF-1 P48 Subunit; Retinoblastoma Binding Protein 4; MSI1 Protein Homolog; RBAP48 Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] Research Area: Epigenetics and Nuclear Signaling,Cancer