KD-Validated Retinoic Acid Receptor Beta Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Retinoic Acid Receptor Beta Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Retinoic Acid Receptor Beta; RAR-Beta; NR1B2; HAP; RARbeta; RRB2; Nuclear Receptor Subfamily 1 Group B Member 2; HBV-Activated Protein; RAR-Epsilon; Retinoic Acid Receptor, Beta Polypeptide; Hepatitis B Virus Activated Protein; Retinoic Acid Receptor, Beta; RARbeta1; MCOPS12 Background: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014] Research Area: Epigenetics and Nuclear Signaling,Signal Transduction,Cancer