KD-Validated RHOC Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated RHOC Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:RHOC; Ras Homolog Family Member C; ARH9; ARHC; Rho-Related GTP-Binding Protein RhoC; Ras Homolog Gene Family, Member C; Rho CDNA Clone 9; H9; Epididymis Secretory Sperm Binding Protein; Small GTP Binding Protein RhoC; RAS-Related Homolog 9; Oncogene RHO H9; RhoC GTPase; RHOH9 Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Research Area: Cancer