KD-Validated RING1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated RING1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Ring Finger Protein 1; RNF1; RING-Type E3 Ubiquitin Transferase RING1; Really Interesting New Gene 1 Protein; E3 Ubiquitin-Protein Ligase RING1; Polycomb Complex Protein RING1; RING Finger Protein 1; EC 2.3.2.27; EC 6.3.2; RING1A Background: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling