KD-Validated RNH1 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated RNH1 Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000 Alternative Names of Immunogen:RNH1; Ribonuclease/Angiogenin Inhibitor 1; RAI; RNH; Placental Ribonuclease Inhibitor; Placental RNase Inhibitor; Ribonuclease Inhibitor; Ribonuclease/Angiogenin Inhibitor; Testicular Tissue Protein Li 164; IIAE12; PRI Background: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010] Research Area: Epigenetics and Nuclear Signaling