KD-Validated Sirtuin 5 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Sirtuin 5 Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:SIRT5; Sirtuin 5; NAD-Dependent Protein Deacylase Sirtuin-5, Mitochondrial; SIR2L5; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 5 (S. Cerevisiae); Sirtuin (Silent Mating Type Information Regulation 2, S.Cerevisiae, Homolog) 5; NAD-Dependent Lysine Demalonylase And Desuccinylase Sirtuin-5, Mitochondrial; Silent Mating Type Information Regulation 2, S.Cerevisiae, Homolog 5; NAD-Dependent Deacetylase Sirtuin-5; Regulatory Protein SIR2 Homolog 5; SIR2-Like Protein 5; Sirtuin Type 5; Sir2-Like 5; EC 2.3.1.- Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010] Research Area: Cardiovascular,Epigenetics and Nuclear Signaling