KD-Validated SMARCE1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated SMARCE1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:SMARCE1; SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1; BAF57; SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily E Member 1; BRG1-Associated Factor 57; SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin E1; Chromatin Remodeling Complex BRG1-Associated Factor 57; CSS5 Background: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling