KD-Validated SPINK5 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated SPINK5 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:SPINK5; Serine Peptidase Inhibitor Kazal Type 5; LEKTI; VAKTI; LETKI; NETS; NS; Lympho-Epithelial Kazal-Type-Related Inhibitor; Lymphoepithelial Kazal-Type-Related Inhibitor; Serine Protease Inhibitor Kazal-Type 5; FLJ21544; FLJ97536; FLJ97596 ; FLJ99794; Serine Protease Inhibitor, Kazal Type 5; DKFZp686K19184; DKFZP686K19184 Background: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] Research Area: Cell Biology