KD-Validated SPOP Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated SPOP Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:SPOP; Speckle Type BTB/POZ Protein; Speckle-Type POZ Protein; BTBD32; TEF2; Roadkill Homolog 1; HIB Homolog 1; NEDMACE; NEDMIDF; NSDVS1; NSDVS2 Background: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling