KD-Validated SRP72 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated SRP72 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:SRP72; Signal Recognition Particle 72; Signal Recognition Particle 72 KDa Protein; Signal Recognition Particle Subunit SRP72; Signal Recognition Particle 72kDa; Signal Recognition Particle 72kD; Epididymis Luminal Protein 103; HEL103; BMFS1; BMFF Background: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012] Research Area: Epigenetics and Nuclear Signaling,Signal Transduction