KD-Validated STAT6 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated STAT6 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:STAT6; Signal Transducer And Activator Of Transcription 6; IL-4-STAT; D12S1644; Signal Transducer And Activator Of Transcription 6, Interleukin-4 Induced; Transcription Factor IL-4 STAT; STAT, Interleukin4-Induced; EC 2.4.1.227; EC 2.7.7.6; IL-4 Stat; STAT6B; STAT6C Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Research Area: Signal Transduction,Epigenetics and Nuclear Signaling,Cancer,Kits/ Lysates/ Other