

KVAb00722-100ul ยท 100ul
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Description
EnkiLife offers the KD-Validated STAU1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:STAU1; Staufen Double-Stranded RNA Binding Protein 1; PPP1R150; STAU; Double-Stranded RNA-Binding Protein Staufen Homolog 1; Protein Phosphatase 1, Regulatory Subunit 150; Staufen, RNA Binding Protein, Homolog 1 (Drosophila); Staufen (Drosophila, RNA-Binding Protein); Staufen, RNA Binding Protein (Drosophila); Staufen, RNA Binding Protein, Homolog 1 Background: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020] Research Area: Signal Transduction,Neuroscience