KD-Validated Superoxide Dismutase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Superoxide Dismutase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:SOD1; Superoxide Dismutase 1; IPOA; Superoxide Dismutase 1, Soluble; Superoxide Dismutase [Cu-Zn]; EC 1.15.1.1; HSod1; ALS1; ALS; Amyotrophic Lateral Sclerosis 1 (Adult); Epididymis Secretory Protein Li 44; Superoxide Dismutase, Cystolic; Cu/Zn Superoxide Dismutase; Indophenoloxidase A; SOD, Soluble; Homodimer; HEL-S-44; STAHP; SOD Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020] Research Area: Signal Transduction,Cell Biology,Cancer,Metabolism,Neuroscience