KD-Validated ARFGAP3 Mouse Oligoclonal Antibody

Description

EnkiLife offers the KD-Validated ARFGAP3 Mouse Oligoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; ICC 1:100-1:1,000 Alternative Names of Immunogen:ARFGAP3; ARF GTPase Activating Protein 3; ADP Ribosylation Factor GTPase Activating Protein 3; ARFGAP1; ADP-Ribosylation Factor GTPase Activating Protein 1; ADP-Ribosylation Factor GTPase-Activating Protein 3; ARF GAP 3 Background: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008] Research Area: Signal Transduction