KD-Validated TANK Binding Kinase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated TANK Binding Kinase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:TBK1; TANK Binding Kinase 1; NAK; Serine/Threonine-Protein Kinase TBK1; NF-Kappa-B-Activating Kinase; TANK-Binding Kinase 1; T2K; NF-KB-Activating Kinase; EC 2.7.11.1; EC 2.7.11; FTDALS4; IIAE8 Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. [provided by RefSeq, Sep 2021] Research Area: Signal Transduction,Epigenetics and Nuclear Signaling,Neuroscience