KD-Validated TANK Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated TANK Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000 Alternative Names of Immunogen:TANK; TRAF Family Member Associated NFKB Activator; I-TRAF; TRAF2; TRAF Family Member-Associated NF-Kappa-B Activator; TRAF-Interacting Protein; ITRAF; TRAF Family Member-Associated NFKB Activator Background: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] Research Area: Signal Transduction,Immunology