

KVAb00847-20ul · 20ul
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Description
EnkiLife offers the KD-Validated TARBP2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:TARBP2; TARBP2 Subunit Of RISC Loading Complex; Trbp; TARBP2, RISC Loading Complex RNA Binding Subunit; RISC-Loading Complex Subunit TARBP2; TAR (HIV-1) RNA Binding Protein 2; Trans-Activation Responsive RNA-Binding Protein; Trans-Activation-Responsive RNA-Binding Protein; TAR (HIV) RNA-Binding Protein TRBP1; TAR (HIV) RNA-Binding Protein 2; TAR RNA Binding Protein 2; TAR RNA-Binding Protein 2; TRBP1; TRBP2; LOQS; TRBP Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008] Research Area: Microbiology,Epigenetics and Nuclear Signaling







