KD-Validated TIA1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated TIA1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:TIA1; TIA1 Cytotoxic Granule Associated RNA Binding Protein; TIA-1; T-Cell-Restricted Intracellular Antigen-1; Cytotoxic Granule Associated RNA Binding Protein TIA1; Nucleolysin TIA-1 Isoform P40; TIA1 Cytotoxic Granule-Associated RNA-Binding Protein; P40-TIA-1 (Containing P15-TIA-1); RNA-Binding Protein TIA-1; P40-TIA-1; ALS26; WDM Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017] Research Area: Cell Biology,Immunology,Epigenetics and Nuclear Signaling,Cancer