KD-Validated Tissue Factor Pathway Inhibitor Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Tissue Factor Pathway Inhibitor Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:TFPI; Tissue Factor Pathway Inhibitor; TFPI1; EPI; Extrinsic Pathway Inhibitor; LACI; TFI; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); Lipoprotein-Associated Coagulation Inhibitor; Anti-Convertin Background: This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016] Research Area: Cardiovascular