KD-Validated TMEM173 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated TMEM173 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:STING1; Stimulator Of Interferon Response CGAMP Interactor 1; STING; ERIS; MITA; Transmembrane; Protein 173; TMEM173; NET23; MPYS; Endoplasmic Reticulum Interferon Stimulator; Stimulator Of Interferon Genes Protein; Endoplasmic Reticulum IFN Stimulator; FLJ38577; HSTING; HMITA; N-Terminal Methionine-Proline-Tyrosine-Serine Plasma Membrane Tetraspanner; Mitochondrial Mediator Of IRF3 Activation; Stimulator Of Interferon Protein; Stimulator Of Interferon Gene; Mediator Of IRF3 Activation; STING-Beta; Sting 1; SAVI Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] Research Area: Immunology,Signal Transduction,Epigenetics and Nuclear Signaling,Cancer