KD-Validated Transmembrane Protein 43 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Transmembrane Protein 43 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:TMEM43; Transmembrane Protein 43; LUMA; DKFZp586G1919; MGC3222; ARVD5; Arrhythmogenic Right Ventricular Dysplasia 5; EDMD7; AUNA2; Protein LUMA; ARVC5; AUNA3; EDMD7 Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008] Research Area: Tags & Cell Markers,Signal Transduction