

KVAb00888-50ul · 50ul
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Description
EnkiLife offers the KD-Validated TRPM7 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:TRPM7; Transient Receptor Potential Cation Channel Subfamily M Member 7; LTRPC7; CHAK1; TRP-PLIK; Long Transient Receptor Potential Channel 7; Channel-Kinase 1; EC 2.7.11.1; LTrpC-7; Transient Receptor Potential Cation Channel, Subfamily M, Member 7; Transient Receptor Potential-Phospholipase C-Interacting Kinase; LTRPC Ion Channel Family Member 7; ALSPDC; LTrpC7; CHAK Background: This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017] Research Area: Neuroscience,Signal Transduction,Metabolism







