KD-Validated Tuberin Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Tuberin Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Tuberin; PPP1R160; TSC4; LAM; Protein Phosphatase 1, Regulatory Subunit 160; Tuberous Sclerosis 2 Protein; Tuberous Sclerosis 2 Background: This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022] Research Area: Cell Biology,Signal Transduction,Epigenetics and Nuclear Signaling,Metabolism