KD-Validated Ubiquitin Specific Peptidase 5 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Ubiquitin Specific Peptidase 5 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:USP5; Ubiquitin Specific Peptidase 5; Isopeptidase T; IsoT; Ubiquitin-Specific-Processing Protease 5; Ubiquitin Carboxyl-Terminal Hydrolase 5; Deubiquitinating Enzyme 5; Ubiquitin Thioesterase 5; Ubiquitin-Specific Protease-5 (Ubiquitin Isopeptidase T); Ubiquitin Specific Peptidase 5 (Isopeptidase T); Ubiquitin Specific Protease 5 (Isopeptidase T); Testicular Tissue Protein Li 218; Ubiquitin Thiolesterase 5; Ubiquitin Isopeptidase T; EC 3.4.19.12; EC 3.1.2.15; ISOT Background: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010] Research Area: Cell Biology,Epigenetics and Nuclear Signaling