KD-Validated Ubiquitination Factor E4A Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Ubiquitination Factor E4A Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:UBE4A; Ubiquitination Factor E4A; KIAA0126; UBOX2; UFD2; E4; Ubiquitination Factor E4A (UFD2 Homolog, Yeast); RING-Type E3 Ubiquitin Transferase E4 A; Ubiquitin Conjugation Factor E4 A; Ubiquitination Factor E4A (Homologous To Yeast UFD2); EC 2.3.2.27; NEDHMS Background: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] Research Area: Epigenetics and Nuclear Signaling,Cell Biology