KD-Validated UFD1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated UFD1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:UFD1; Ubiquitin Recognition Factor In ER Associated Degradation 1; UFD1L; Ubiquitin Recognition Factor In ER-Associated Degradation Protein 1; UB Fusion Protein 1; Ubiquitin Fusion Degradation Protein 1 Homolog; Ubiquitin Fusion Degradation 1 Like (Yeast); Ubiquitin Fusion Degradation Protein 1; Ubiquitin Fusion Degradation 1-Like; Ubiquitin Fusion Degradation 1 Like Background: The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009] Research Area: Cell Biology