KD-Validated Vinculin Rabbit Polyclonal Antibody

Description

EnkiLife offers the KD-Validated Vinculin Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500 Alternative Names of Immunogen:VCL; Vinculin; Metavinculin; VINC; MV; Epididymis Secretory Sperm Binding Protein; Epididymis Luminal Protein 114; Meta-Vinculin; HEL114; CMD1W; CMH15; MVCL Background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Cardiovascular,Isotype/Loading Controls