KD-Validated WWOX Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated WWOX Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:WWOX; WW Domain Containing Oxidoreductase; SDR41C1; WOX1; FOR; WW Domain-Containing Oxidoreductase; Short Chain Dehydrogenase/Reductase Family 41C Member 1; Fragile Site FRA16D Oxidoreductase; Short Chain Dehydrogenase/Reductase Family 41C, Member 1; WW Domain-Containing Protein WWOX; EC 1.1.1.-; D16S432E; EC 1.1.1; HHCMA56; PRO0128; EIEE28; FRA16D; SCAR12; DEE28 Background: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Research Area: Cell Biology,Neuroscience,Epigenetics and Nuclear Signaling,Cancer