KD-Validated XPD Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated XPD Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ERCC2; ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit; EM9; XPD; Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2; General Transcription And DNA Repair Factor IIH Helicase Subunit XPD; TFIIH Basal Transcription Factor Complex Helicase XPB Subunit; TFIIH Basal Transcription Factor Complex 80 KDa Subunit; Xeroderma Pigmentosum Group D-Complementing Protein; Excision Repair Cross-Complementation Group 2; Xeroderma Pigmentosum Complementary Group D; DNA Repair Protein Complementing XP-D Cells; Basic Transcription Factor 2 80 KDa Subunit; DNA Excision Repair Protein ERCC-2; TFIIH 80 KDa Subunit; TFIIH Subunit XPD; MGC102762; MGC126218; MGC126219; TFIIH P80; BTF2 P80; CXPD; MAG; Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 Protein; TFIIH Basal Transcription Factor Complex Helicase XPD Subunit; TFIIH Basal Transcription Factor Complex Helicase Subunit; EC 3.6.4.12; EC 3.6.1; COFS2; TFIIH; TTD1; XPDC; TTD Background: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Research Area: Epigenetics and Nuclear Signaling