KD-Validated YTHDC2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated YTHDC2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:YTHDC2; YTH N6-Methyladenosine RNA Binding Protein C2; 3'-5' RNA Helicase YTHDC2; YTH Domain Containing 2; DKFZp564A186; FLJ10053; FLJ2194; HYTHDC2; Probable ATP-Dependent RNA Helicase YTHDC2; CsA-Associated Helicase-Like Protein; YTH Domain-Containing Protein 2; EC 3.6.4.13; EC 3.6.1; CAHL Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016] Research Area: Cell Biology