KD-Validated ZNF346 Mouse Oligoclonal Antibody

Description

EnkiLife offers the KD-Validated ZNF346 Mouse Oligoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ZNF346; Zinc Finger Protein 346; JAZ; Zfp346; Just Another Zinc Finger Protein; Double-Stranded RNA-Binding Zinc Finger Protein JAZ Background: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015] Research Area: Epigenetics and Nuclear Signaling,Cell Biology