GENERAL CATALOGUE
KD6001
HY-P991566 · 1 mg
MedChemExpress · Cat: HY-P991566
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medchemexpress.com/kd6001.htmlCatalog No: HY-P991566
CAS No: 2983061-18-1
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
KD6001 is a humanized IgG1? monoclonal antibody, targeting CTLA4. KD6001 significantly disrupts CTLA-4 interactions with CD80 IC50: 16 ng/mL and CD86. KD6001 enhances IL-2 and IFN? expression in PHA-activated human lymphocytes and exhibits potent antitumor effects. KD6001 effectively inhibits tumor growth in MC38, B16, and Hepa1-6 tumor mice model. KD6001 can be used for cancers research, such as advanced melanoma, hepatocellular carcinoma and liver cancer.
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