GENERAL CATALOGUE
KDM5A-IN-1
HY-100014 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100014
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Manufacturer product page
medchemexpress.com/KDM5A-IN-1.htmlCatalog No: HY-100014
CAS No: 1905481-36-8
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 KDM5 inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes 1A, 2B, 3B, 4C, 6A, 7B .
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