GENERAL CATALOGUE
KDM5B-IN-4
HY-149091 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-149091
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Manufacturer product page
medchemexpress.com/kdm5b-in-4.htmlCatalog No: HY-149091
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
KDM5B-IN-4 compound 11ad is a lysine demethylase 5B KDM5B inhibitor with an IC50 of 0.025 ?M KDM5B-IN-4 increases substrate H3K4me1/2/3 level by inhibiting KDM5B in PC-3 cells. KDM5B-IN-4 downregulates PI3K/AKT. KDM5B-IN-4 reduces tumor volume in mice and shows less toxic to organs.
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