GENERAL CATALOGUE
KDOAM-25 trihydrochloride
HY-102047A · 50 mg
MedChemExpress · Cat: HY-102047A
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medchemexpress.com/kdoam-25-trihydrochloride.htmlCatalog No: HY-102047A
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 KDM5 inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells.