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Keap1-Nrf2-IN-25
GENERAL CATALOGUE

Keap1-Nrf2-IN-25

HY-168922 · 50 mg

MedChemExpress · Cat: HY-168922

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Catalog No: HY-168922
CAS No: 3100306-80-4
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

Keap1-Nrf2-IN-25 Compound 19 is a potent Keap1-Nrf2 inhibitor IC50 of 0.55 ?M with Keap1 binding affinity Kd of 0.50 ?M . Keap1-Nrf2-IN-25 activates Nrf2, reduces ROS and pro-inflammatory cytokines IL-1?, IL-6 . Keap1-Nrf2-IN-25 exerts protective effects against DSS HY-116282 -induced colitis.

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