GENERAL CATALOGUE
Ki16425
HY-13285 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13285
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Catalog No: HY-13285
CAS No: 355025-24-0
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ki16425 Debio 0719 is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 ?M and 0.93 ?M, respectively. Ki16425 Debio 0719 reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein YAP /TAZ in HEK293A cells.
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