GENERAL CATALOGUE
KIF2C-IN-1
HY-173522 · 5 mg
MedChemExpress · Cat: HY-173522
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Catalog No: HY-173522
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
KIF2C-IN-1 Compound 7S9 is a selective and potent small-molecule KIF2C inhibitor. KIF2C-IN-1 stabilizes the KIF2C-tubulin interaction, blocking the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel HY-B0015 in paclitaxel-resistant triple-negative breast cancer TNBC cells and significantly reduces tumor growth combined with Paclitaxel in mouse models.
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