GENERAL CATALOGUE
KIM-161
HY-172964 · 50 mg
MedChemExpress · Cat: HY-172964
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medchemexpress.com/kim-161.html
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Catalog No: HY-172964
CAS No: 2559686-28-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
KIM-161 is a PIK3CA inhibitor. KIM-161 has significant antiproliferative activity with IC50 values of 1.428 and 1.562 AAasAasAAmuM against PI3KCA mutant breast cancer MCF7 and T47D cells, respectively. KIM-161 induces apoptosis and cell cycle arrest by inhibiting the PI3K/AKT/mTOR signaling pathway and inducing ROS production. KIM-161 can be used to study breast cancer and its PI3KCA mutant subtypes.
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