GENERAL CATALOGUE
KL1333
HY-128895 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128895
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Catalog No: HY-128895
CAS No: 1800405-30-4
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
KL1333, a derivative of ?-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD P H:quinone oxidoreductase 1 NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures.
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